Chlamydia Treatment: Effective Options and Recovery
Learn about antibiotic treatments, recovery time, and follow-up care for chlamydia infections.
Medically reviewed by healthcare professionals
Last updated: April 2025
Treatment Overview
Chlamydia is a bacterial infection that can be effectively treated with antibiotics. When taken correctly, antibiotics are highly effective at eliminating the infection. The key to successful treatment is:
- Taking all medication exactly as prescribed
- Abstaining from sexual activity until treatment is complete
- Ensuring all sexual partners are also tested and treated
- Getting retested if symptoms persist or return
Treatment Success Rate
When taken properly, antibiotic treatment for chlamydia has a success rate of more than 95%. However, reinfection is common if partners aren't treated or if treatment isn't completed.
Antibiotic Options for Chlamydia
Healthcare providers typically prescribe one of the following antibiotics to treat chlamydia:
Azithromycin
Dosage: Usually given as a single dose (1 gram)
How it works: Azithromycin works by stopping the growth of bacteria by preventing the bacteria from making proteins that are essential for their survival.
Advantages: Convenient single-dose treatment, which can improve compliance since you only need to take it once.
Potential side effects: Nausea, vomiting, diarrhea, abdominal pain
Doxycycline
Dosage: Typically prescribed as 100 mg taken twice daily for 7 days
How it works: Doxycycline prevents bacteria from producing proteins necessary for their growth and reproduction.
Advantages: Highly effective and may be preferred for certain types of chlamydial infections.
Potential side effects: Sun sensitivity (photosensitivity), upset stomach, diarrhea, heartburn
Important: Doxycycline should not be used by pregnant women or children under 8 years old.
Alternative antibiotics that may be prescribed in certain situations include:
- Erythromycin - Often used during pregnancy if azithromycin is not suitable
- Levofloxacin - May be used if other antibiotics are not suitable
- Ofloxacin - An alternative option for those who cannot take first-line treatments
Special Treatment Considerations
Treatment During Pregnancy
Pregnant women with chlamydia require treatment to prevent transmission to the baby during birth. Safe options include:
- Azithromycin - Generally considered safe during pregnancy
- Erythromycin - Alternative when azithromycin is not suitable
- Amoxicillin - May be prescribed in some cases
Doxycycline and fluoroquinolones (like levofloxacin) are not recommended during pregnancy.
Treatment for HIV-Positive Patients
People with HIV and chlamydia typically receive the same treatment as those who are HIV-negative. However, they may require more careful monitoring and follow-up testing.
Treatment for Complicated Infections
More complicated infections, such as pelvic inflammatory disease (PID) or epididymitis, may require:
- Longer courses of antibiotics
- Different combinations of medications
- Possible hospitalization for severe cases
During and After Treatment
Recovery Timeline
- Symptoms should improve within 1-2 weeks of starting treatment.
- The infection is usually cleared within 7 days of completing the full course of antibiotics.
- You should abstain from sexual activity for 7 days after completing treatment (single-dose azithromycin) or until completing the full course of antibiotics (doxycycline).
Important Guidelines During Treatment
- Take all medication exactly as prescribed, even if symptoms disappear
- Abstain from sexual intercourse until treatment is complete
- Inform all sexual partners from the past 60 days that they should get tested and treated
- Follow up with your healthcare provider if symptoms persist after treatment
When to Contact Your Healthcare Provider
Contact your healthcare provider if:
- Symptoms don't improve within 1-2 weeks of starting treatment
- Symptoms return after treatment is complete
- You experience severe side effects from medication
- You vomit shortly after taking a single-dose treatment (it may not have been absorbed)
Partner Notification and Treatment
Partner notification and treatment are crucial aspects of chlamydia management. Without treating partners, reinfection is likely.
Guidelines for Partner Notification:
- All sexual partners from the past 60 days should be notified, tested, and treated
- Some healthcare providers offer expedited partner therapy (EPT), where they provide treatment for partners without examination
- Anonymous notification services are available in many areas if you're uncomfortable notifying partners yourself
Preventing Reinfection
Many people get reinfected with chlamydia from an untreated partner. Ensuring all partners are treated is the best way to prevent reinfection.
Follow-up Testing
For most uncomplicated chlamydia infections, follow-up testing (called a "test of cure") is not required if treatment is completed as prescribed and symptoms resolve.
However, retesting is recommended in the following situations:
- 3 months after treatment for all patients (due to the high risk of reinfection)
- If symptoms persist or recur after treatment
- If you suspect your partner hasn't been treated
- If you didn't complete the treatment as prescribed
- If you are pregnant (test of cure 3-4 weeks after treatment)
Sources & References
1. Centers for Disease Control and Prevention. (2021). Sexually Transmitted Infections Treatment Guidelines, 2021. Morbidity and Mortality Weekly Report, 70(4), 1-187.
2. World Health Organization. (2022). Guidelines for the management of symptomatic sexually transmitted infections.
3. British Association for Sexual Health and HIV. (2018). UK National Guideline for the Management of Infection with Chlamydia trachomatis.
4. American College of Obstetricians and Gynecologists. (2020). Treatment of Sexually Transmitted Infections in Pregnant Women.
5. Mayo Clinic. (2022). Chlamydia trachomatis - Diagnosis and Treatment.